pentobarbital will lower the extent or impact of etravirine by influencing hepatic enzyme CYP2C9/10 metabolism. Use Warning/Watch.pentobarbital will decrease the extent or outcome of gefitinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.Roughly 25 to 50 per cent of the dose of aprobarbital or phenobarbital is eradicated unchanged wit